JSGH-20水平式干法制粒機(jī)工作原理(Working Theory of Dry TypeGranulation Facility):
根據(jù)機(jī)械擠壓造粒工藝原理,將配置好的,具有一定結(jié)晶水的干粉狀或微細(xì)晶體狀原料,擠壓成薄片,后經(jīng)造粒系統(tǒng),通過(guò)篩網(wǎng)制成所需大小的顆粒。
原料可通過(guò)手工上料或真空上料機(jī)加入料斗,經(jīng)送料螺桿輸送和壓縮.被推至兩擠壓輥輪的咬入角:通過(guò)壓輥,將原料擠壓成薄片。物料所需的壓力通過(guò)液壓裝置線性傳送給壓輥,液壓裝置可保持一定的預(yù)壓力, 垂直排列的壓輥可保證物料密度的一致性。根據(jù)不同顆粒度要求,設(shè)備造粒系統(tǒng)中的篩網(wǎng)目數(shù)大小可相互更換。
According to the technical theory ofmechanical extrusion for granulation, a wel-prepared powdery or finely crystallinematerial with crystal water is laminatedand made into particles of required size bymeans of screen in the granulation system.
The material may be fed into the bucketby hand or vacuum feeder, conveyed andcompressed in the feed screw, and pushedinto bite angle of two extrusion wheels.The material is laminated by therollers.The pressure required by material islinearly delivered from hydraulic device torollers. The hydraulic device can maintaincertain pre-pressure and the verticallyarranged rollers can guarantee theconsistent density of According to different required grainmaterial.sizes, the screens with different meshes inthe granulation system can be interchanged.
JSGH-20水平式干法制粒機(jī)干法制粒優(yōu)點(diǎn)(Advantages of Dry TypeGranulation):
將粉體或微細(xì)晶體原材料直接制成滿足用戶(hù)要求的顆粒狀產(chǎn)品,無(wú)需任何中間體和添加劑,造粒后產(chǎn)品粒度均勻,堆積密度顯著增加,改善流動(dòng)性,既控制'了粉塵飛揚(yáng),又減少粉料浪費(fèi)。便于貯存和運(yùn)輸,可控制溶解度、孔隙率和比表面積等。
本機(jī)在濕式造粒法中難生產(chǎn)的抗生物質(zhì)。膠囊填充用顆粒及制造藥片的造粒上能發(fā)揮很大的作用。
Powder or fine crystal can be directlymade into granules to the satisfaction ofusers, without requiring any intermediate oradditive. The granules have even grain sizewith considerably increasing bulk density.This can improve the fluidity, inhibit theraised dust and reduce the waste of powder.
It is easy to store and transport andallows the control of solubility, porosity andspecific surface area.The granulator generates the antibioticThe granulator generates the antibiotictype granulation. .type granulation. .It can play an importantrolein thein thethe granulation for pills.
JSGH-20水平式干法制粒機(jī)應(yīng)用范圍(Applcability):
在制藥工業(yè)中,廣泛涉及到對(duì)各種活性的藥品原料以及-種或多種賦形劑的加工處理。這些原料藥大部分是細(xì)的粉末,并且這些粉末粒徑大小不一,密度不勻,流動(dòng)性差,易分層。這些原料藥必須經(jīng)過(guò)制粒工藝處理.才能.被用于壓片、膠囊填充或其他藥物加工工序。干法制粒因其具有多種優(yōu)勢(shì).特別適用于在濕.熱條件下不穩(wěn)定的藥物的制粒。
The pharmaceutical industry oftenprocesses the medicine materials of variousactivities and one or several excipients.Most of bulk drugs are finely powdery indifferent grain sizes, uneven density, poorfluidity and easy stratification. They must begranulated before being laminated, flled intocapsules or processed in other ways. Forits various advantages, dry type granulationis particularly suitable for the granulation ofdrugs unstable under wet and hot conditions.
JSGH-20水平式干法制粒機(jī)特別說(shuō)明(Special Note):
在產(chǎn)品設(shè)計(jì)和生產(chǎn)過(guò)程中,我們遵循了美國(guó)FDA、GMP思想。任何一臺(tái)設(shè)備在生產(chǎn)過(guò)程中,皆具備GMP控制范圍;在設(shè)計(jì)過(guò)程中,任何一臺(tái)設(shè)備皆在GMP內(nèi)創(chuàng)新構(gòu)思。所有的非金屬材料均符合GMP &FDA標(biāo)準(zhǔn)。
送料量、壓力、壓輥間隙、片厚、整粒間.隙、片硬度等工藝參數(shù)通過(guò)邏輯運(yùn)算、數(shù)理統(tǒng)計(jì)建數(shù)據(jù)模型,并形成科學(xué)系統(tǒng)關(guān)系。
In the machine design and .manufacturing process, we follow theFDA GMP idea. Any equipment in themanufacturing process has GMP controlrange,In the designing process, anyequipment is in GMP innovation concept.All non-metallic materials comply withGMP&FDA standards.
The process parameters such as feedamount,pressure roller gap, slicethickness,grinding gap and slice .hardness were established to formscientific system relationship throughlogical operation and mathematicalstatistics.
JSGH-20水平式干法制粒機(jī)設(shè)計(jì)特點(diǎn)(Design Features):
1、專(zhuān)門(mén)用于研究、實(shí)驗(yàn)室小批試樣;
2、論證某些含結(jié)晶水的物料.能否采用干法制粒工藝;
3、需100克左右的物料,了解其物料可壓成形性能,及時(shí)調(diào)正配方(含水量、輔料等).改進(jìn)制粒工藝路線。測(cè)試必要的技術(shù)參數(shù).為開(kāi)發(fā)新產(chǎn)品和直接投入生產(chǎn)提供可靠理論依據(jù);
4、本機(jī)適用于制藥.化工.食品行業(yè)的制粒。
1、Special for research and s ample test inlaboratory;
2、Verify whether some materials with crystalwater are suitable for dry type granulation;
3、Take around 100g material to learn aboutthe pressing and forming performance ofmaterial to timely adjust the prescription(water content, auxiliary material, etc.),improve the granulation process and testthe necessary technical parameters, inorder to provide the reliable theoreticalbasis for developing new products anddirectly putting into production;
4、Suitable for granulation in pharmaceutical,chemical and food industries.
JSGH-20水平式干法制粒機(jī)技術(shù)參數(shù)(Technical Parameters):
生產(chǎn)能力
●批處理量:200g
●連續(xù)生產(chǎn)能力: 25Kg/h
●可成型粒度: 0.2-2 mm
●操作系統(tǒng):西門(mén)子S7-200 SMART
●整機(jī)功率: 2.5Kw AC380,50HZ ( CN )
●擠壓輪規(guī)格:100 X 40 mm
●成型壓力: 8 T
●攪拌轉(zhuǎn)速: 1-100轉(zhuǎn)/分
●送料轉(zhuǎn)速: 1-130轉(zhuǎn)/分
●擠壓轉(zhuǎn)速: 1-28轉(zhuǎn)/分
●破碎轉(zhuǎn)速: 1-110轉(zhuǎn)/分
●制粒轉(zhuǎn)速: 1-150轉(zhuǎn)/分
●整機(jī)重量: 800Kg
●外形尺寸: 1100X 1000 X 1600mm
●物料接觸部分材質(zhì): SUS 304 & 316L
●擠壓輪材質(zhì): 2Cr13、3Cr13、合金鋼
●與物料接觸部分密封材質(zhì):聚四氟乙烯
Production Capacity
●Batching:200g
●Continuous producion capacity:25kg/h
●Grain size: 0.2-2 mm
●Operation system: Siemens S7-200 SMART
●Installation power: 2.5Kw ,AC380,50HZ ( CN
●Roll dimension: 100 X 40 mm
●Maximum forming pressure: 8 T
●Scrapper rotational speed: 1-100r/m
●Screw feeder rotational speed: 1-130r/m
●Roll rotational speed: 1-28r/m
●Flake breaker rotational speed: 1-110r/m
●Fime granulator rotational speed: 1-150r/m
●Dead weight: 800Kg
●Machine dimension: 1100 X 1000 X 1600 mm
● Material: SUS 304 &316L
●Material of roller: 2Cr13、 3Cr13、 alloy steel
●Axial gasket in contact with product: PTFE